BDBM50559388 CHEMBL4749146::US20250162994, Example 14

SMILES ONC(=O)c1ccc(CCCN2CCC(CN[C@H]3C[C@@H]3c3ccccc3)CC2)cc1

InChI Key InChIKey=HACUHRDPZRXYSI-UHFFFAOYSA-N

Data  19 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50559388   

TargetHistone deacetylase 8(Human)
Jubilant Therapeutics India

Curated by ChEMBL
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 71nMAssay Description:Inhibition of human HDAC8 using RHKAcKAc as substrate by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Jubilant Epicore

US Patent
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 69nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Jubilant Epicore

US Patent
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
In Depth
Date in BDB:
9/19/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Jubilant Epicore

US Patent
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 48nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Jubilant Epicore

US Patent
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 5nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Jubilant Therapeutics India

Curated by ChEMBL
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jubilant Therapeutics India

Curated by ChEMBL
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Jubilant Therapeutics India

Curated by ChEMBL
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Jubilant Therapeutics India

Curated by ChEMBL
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Jubilant Therapeutics India

Curated by ChEMBL
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 3.43E+3nMAssay Description:Inhibition of human HDAC9 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Jubilant Epicore

US Patent
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 6nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Jubilant Therapeutics India

Curated by ChEMBL
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of human HDAC7 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Jubilant Therapeutics India

Curated by ChEMBL
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Jubilant Therapeutics India

Curated by ChEMBL
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 7.47E+3nMAssay Description:Inhibition of human HDAC3/NCOR2 using RHKKAc as substrate by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Jubilant Therapeutics India

Curated by ChEMBL
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 3.95E+3nMAssay Description:Inhibition of human HDAC2 using RHKKAc as substrate by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Jubilant Therapeutics India

Curated by ChEMBL
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human HDAC1 using RHKKAc as substrate by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Jubilant Epicore

US Patent
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 69nMAssay Description:Inhibition of human HDAC6 (unknown origin) using RHKKAc as substrate by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Jubilant Epicore

US Patent
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 69nMAssay Description:Inhibition of human HDAC6 (unknown origin) using RHKKAc as substrate by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Jubilant Epicore

US Patent
LigandPNGBDBM50559388(CHEMBL4749146 | US20250162994, Example 14)
Affinity DataIC50: 6nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed