BDBM50559332 CHEMBL4797361

SMILES C[C@H](Nc1ncnc(N)c1C#N)c1c(C)c(=O)n2cc(F)ccc2c1-c1ccc(F)cc1

InChI Key InChIKey=AZHBYHIZGYWPKA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50559332   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Lupin

Curated by ChEMBL

LigandBDBM50559332(CHEMBL4797361)Copy SMILESCopy InChI

Affinity DataIC50: 114nMAssay Description:Inhibition of PI3Kdelta in human Raji cells assessed as reduction in phosphorylation of AKT at 473 measured after 2 hr by alpha screen assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/27/2022
Entry Details Article
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