BDBM50559029 CHEMBL4792549

SMILES COc1ccc2nc(cc(-c3nnc(SCC(=O)Nc4ccc(cc4)C(\C)=N/O)n3-c3ccccc3)c2c1)-c1ccc(Cl)cc1

InChI Key InChIKey=USVGKDWIRJLLJA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50559029   

TargetSignal transducer and activator of transcription 3(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50559029(CHEMBL4792549)
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of STAT3 in human SB-590885-sensitive 451Lu cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50559029(CHEMBL4792549)
Affinity DataIC50: 4.05E+4nMAssay Description:Inhibition of STAT3 in human SB-590885-resistant 451Lu cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50559029(CHEMBL4792549)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of STAT3 in human SB-590885-sensitive MEL1617 cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
The University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50559029(CHEMBL4792549)
Affinity DataIC50: 3.52E+4nMAssay Description:Inhibition of STAT3 in human SB-590885-resistant MEL1617 cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed