BDBM50558608 CHEMBL4795179

SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)n1c(C)nnc1C(C)C)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccc(NC(=O)COCC(=O)NCCCCCCCNC(=O)COCC(=O)NC)cc1

InChI Key InChIKey=YMPXNWVXTASQGZ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50558608   

TargetC-C chemokine receptor type 5(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50558608(CHEMBL4795179)
Affinity DataIC50: 622nMAssay Description:Antagonist activity at CCR5 receptor in human MOLT4 cells transfected with Gqi5 assessed as inhibition of RANTES-induced calcium mobilization incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Crab-eating macaque)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50558608(CHEMBL4795179)
Affinity DataKi:  151nMAssay Description:Displacement of [125I]MIP-1alpha from CCR5 receptor in rhesus monkey membrane incubated for 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed