BDBM50558488 CHEMBL4794972

SMILES Cc1c(Br)cc(NC(=O)C(c2ccccc2)S(O)(=O)=O)cc1Br

InChI Key InChIKey=DWUBYIFZVUOBSF-UHFFFAOYSA-N

Data  50 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 50 hits for monomerid = 50558488   

LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PTPbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of HePTP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of LYP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SHP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of TC-PTP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His-tagged full length mouse LMW-PTP expressed in Escherichia coli BL21(DE3) by SDS PAGE based mass spectrometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 5.29E+3nMAssay Description:Inhibition of His-tagged human LMW-PTP expressed in Escherichia coli BL21 at 10 uM using pNPP as substrate incubated for 10 mins by microplate reader...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of PEST(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CD45 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of LAR(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PTPalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PTPH1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PTPgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PTPepsilon (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PTPsigma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PTPmu (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MKP3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetDual specificity protein phosphatase 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of VHR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetDual specificity protein phosphatase 23(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of VHZ (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CDC14A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of SSU72 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of PP5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal His-tagged full length rat LMW-PTP expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged PTPbeta (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged SHP2 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged PTP1B (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged TC-PTP (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged SHP1 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged LYP (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged HePTP (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged PTP-MEG2 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged FAP1 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 7.23E+4nMAssay Description:Inhibition of His-tagged PTP-PEST (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged CD45 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged LAR (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged PTPalpha (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 5.29E+3nMAssay Description:Inhibition of His-tagged LMW-PTP isoform A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged PTPgamma (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged PTPepsilon (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged PTPsigma (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged PTPmu (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged MKP3 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged VHR (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 23(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged VHZ (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged SSu72 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetType II inositol 1,4,5-trisphosphate 5-phosphatase(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged PP5 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of FAP-1(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed