BDBM50557987 CHEMBL4777832

SMILES CCCCC(NC1=NS(=O)(=O)c2ccccc12)C(=O)NCC(NC(=O)CC1(CCCCC1)NC(=O)C(C1CC1)n1cc(CC2CCCCC2)nn1)C(N)=O

InChI Key InChIKey=XVZGZFBJLVCZEO-UHFFFAOYSA-N

Data  2 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50557987   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50557987(CHEMBL4777832)
Affinity DataKd:  120nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli assessed as dissociation constant...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50557987(CHEMBL4777832)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of recombinant human TCPTP (1 to 317 residues) expressed in Escherichia coli using DifMup as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM50557987(CHEMBL4777832)
Affinity DataKi:  1.68E+4nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using DifMup as substrate preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed