BDBM50557721 CHEMBL4786845

SMILES CNS(=O)(=O)c1ccc(C(=O)Nc2cccc(c2)S(=O)(=O)NC(C)(C)C)c(c1)N1CCC2(CC2)CC1

InChI Key InChIKey=WKYJWAPZYJNPGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50557721   

TargetKinesin-like protein KIF18A(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50557721(CHEMBL4786845)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant His-tagged human KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed