BDBM50557678 CHEMBL4754084

SMILES C[C@H](NC(=O)c1cc(nn1C)C(F)(F)F)c1nc(no1)-c1ccnc(c1)C(F)F

InChI Key InChIKey=MCURJTIQCCBRFF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557678   

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557678(CHEMBL4754084)
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Mouse)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557678(CHEMBL4754084)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of recombinant wild type mouse KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed