BDBM50557666 CHEMBL4786255

SMILES C[C@H](NC(=O)c1cc(nn1C)C(F)(F)F)c1nc(no1)-c1ccnc(C)c1

InChI Key InChIKey=JOIIFBPFECVQDT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557666   

TargetPotassium channel subfamily T member 1(Human)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557666(CHEMBL4786255)
Affinity DataIC50: 165nMAssay Description:Inhibition of recombinant wild type human KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPotassium channel subfamily T member 1(Mouse)
Praxis Precision Medicines

Curated by ChEMBL
LigandPNGBDBM50557666(CHEMBL4786255)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of recombinant wild type mouse KNa1.1 expressed in human HEK-TREX cells at -80 mV holding potential by automated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed