BDBM50557606 CHEMBL4791213

SMILES CC(C)(F)CCCNc1ncc(C(N)=O)c(NC2(CO)CC2)n1

InChI Key InChIKey=UXVFUQUYAYWCMO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50557606   

TargetNicotinamide N-methyltransferase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50557606(CHEMBL4791213)
Affinity DataIC50: 74nMAssay Description:Inhibition of full length N-terminal His-tagged human NNMT using nicotinamide as substrate incubated for 2 hrs in presence of S-5'adenosyl-L-methioni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Mouse)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50557606(CHEMBL4791213)
Affinity DataIC50: 21nMAssay Description:Inhibition of mouse NNMT using nicotinamide as substrate incubated for 2 hrs in presence of S-5'adenosyl-L-methionine by RapidFire Mass spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetNicotinamide N-methyltransferase(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50557606(CHEMBL4791213)
Affinity DataIC50: 74nMAssay Description:Inhibition of human NNMTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed