BDBM50557572 CHEMBL4792690

SMILES COc1ccc(Nc2nc(\C=C\c3ccccc3)nc3ccccc23)cc1

InChI Key InChIKey=AIPDYBCWUMJJDC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557572   

TargetProstaglandin G/H synthase 1(Sheep)
Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50557572(CHEMBL4792690)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50557572(CHEMBL4792690)
Affinity DataIC50: 3.73E+4nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 production using 10 uM arachidonic acid as substrate preincubated with enzyme for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed