BDBM50556894 CHEMBL4746717::US11299480, Example 51

SMILES Fc1c(F)c(F)c(c(F)c1F)S(=O)(=O)N1CC[C@@H]1C(=O)N(Cc1ccc(cc1)C1CCCCC1)c1ccc(cc1)-c1nnn[nH]1

InChI Key InChIKey=UDQCHJWZYUNEMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50556894   

TargetSignal transducer and activator of transcription 3(Mouse)
University of Hawaii Cancer Center

Curated by ChEMBL
LigandPNGBDBM50556894(CHEMBL4746717 | US11299480, Example 51)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Hawaii

US Patent
LigandPNGBDBM50556894(CHEMBL4746717 | US11299480, Example 51)
Affinity DataIC50: 1.36E+3nMAssay Description:Nuclear extract preparations and DNA-binding activity/electrophoretic mobility shift assay (EMSA) were carried out as previously described (Zhang X, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2022
Entry Details
Go to US Patent