BDBM50556172 CHEMBL4743540

SMILES [#6]-[#8]-c1ccc(Br)cc1S(=O)(=O)[#7]-c1ccc2-[#7]-[#6](=O)\[#6](=[#6](/[#6])-[#6])-c2c1

InChI Key InChIKey=VLMANYNJKKOADM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50556172   

TargetBromodomain-containing protein 4(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50556172(CHEMBL4743540)
Affinity DataIC50: 23nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) preincubated for 15 mins followed by peptide addition and measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50556172(CHEMBL4743540)
Affinity DataIC50: 21nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) preincubated for 15 mins followed by peptide addition and measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50556172(CHEMBL4743540)
Affinity DataIC50: 39nMAssay Description:Inhibition of BRD2 BD1 (unknown origin) preincubated for 15 mins followed by peptide addition and measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50556172(CHEMBL4743540)
Affinity DataIC50: 22nMAssay Description:Inhibition of BRD2 BD2 (unknown origin) preincubated for 15 mins followed by peptide addition and measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed