BDBM50556138 CHEMBL4757618

SMILES CC(C)(C)OC(=O)N1CCOCCOc2cc(ccc2C(O)=O)-c2cnn3ccc1nc23

InChI Key InChIKey=PZILEJGYWZTBCD-UHFFFAOYSA-N

Data  5 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50556138   

TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556138(CHEMBL4757618)
Affinity DataKd:  82nMAssay Description:Binding affinity to N-terminal His6-tagged CK2alpha (1 to 337 residues) (unknown origin) expressed in BL21(DE3) cells by isothermal titration calorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556138(CHEMBL4757618)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T cells measured after 2 hrs by NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556138(CHEMBL4757618)
Affinity DataIC50: 7.39E+3nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T cells measured after 2 hrs by Nano...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556138(CHEMBL4757618)
Affinity DataIC50: 40nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha expressed in HEK293T permeabilized cells measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha'(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556138(CHEMBL4757618)
Affinity DataIC50: 771nMAssay Description:Displacement of fluorescent tracer from full-length human C-terminal NanoLuc-tagged CK2alpha' expressed in HEK293T permeabilized cells measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50556138(CHEMBL4757618)
Affinity DataIC50: 40nMAssay Description:Inhibition of CK2alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed