BDBM50555996 CHEMBL4746286

SMILES OC(=O)C[C@H](C(=O)N1CC[C@@H](CCc2ccc3CCCNc3n2)C1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=NUPIGKKRXBENIY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50555996   

TargetIntegrin alpha-V/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50555996(CHEMBL4746286)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of integrin alphavbeta3 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50555996(CHEMBL4746286)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of integrin alphavbeta5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50555996(CHEMBL4746286)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alphavbeta3 integrin stably expressed in human K562 cells assessed as inhibition of cell adhesion to GST-LAP1 incubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50555996(CHEMBL4746286)
Affinity DataIC50: 794nMAssay Description:Inhibition of human alphavbeta5 integrin stably expressed in human K562 cells assessed as inhibition of cell adhesion to vitronectin incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed