BDBM50555995 CHEMBL4792845

SMILES CC(=C)c1cccc(c1)[C@H](CC(O)=O)C(=O)N1CC[C@@H](CCc2ccc3CCCNc3n2)C1

InChI Key InChIKey=HLYAJAMUFRQZFN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50555995   

TargetIntegrin alpha-V/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50555995(CHEMBL4792845)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of integrin alphavbeta3 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50555995(CHEMBL4792845)
Affinity DataIC50: 5nMAssay Description:Inhibition of integrin alphavbeta5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50555995(CHEMBL4792845)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alphavbeta3 integrin stably expressed in human K562 cells assessed as inhibition of cell adhesion to GST-LAP1 incubated for 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50555995(CHEMBL4792845)
Affinity DataIC50: 316nMAssay Description:Inhibition of human alphavbeta5 integrin stably expressed in human K562 cells assessed as inhibition of cell adhesion to vitronectin incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed