BDBM50555917 CHEMBL4764453

SMILES CCCCCC1=CC(=O)C=C(OC)C1=N

InChI Key InChIKey=BVSIQUZJRPUQTJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50555917   

TargetProstaglandin G/H synthase 1(Sheep)
Institute of Experimental Botany of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50555917(CHEMBL4764453)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institute of Experimental Botany of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50555917(CHEMBL4764453)
Affinity DataIC50: 5.82E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Institute of Experimental Botany of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50555917(CHEMBL4764453)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed