BDBM50555910 CHEMBL469433

SMILES CCCCCCCCCCCC1=CC(=O)C=C(OC)C1=O

InChI Key InChIKey=LRYVDYNQYBMNJP-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50555910   

TargetProstaglandin G/H synthase 1(Sheep)
Institute of Experimental Botany of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50555910(CHEMBL469433)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Institute of Experimental Botany of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50555910(CHEMBL469433)
Affinity DataIC50: 570nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Institute of Experimental Botany of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50555910(CHEMBL469433)
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Institute of Experimental Botany of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50555910(CHEMBL469433)
Affinity DataIC50: 800nMAssay Description:Competitive inhibition of ovine COX-1 assessed as reduction in PGE2 level using 50 nM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Institute of Experimental Botany of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50555910(CHEMBL469433)
Affinity DataIC50: 2.77E+3nMAssay Description:Competitive inhibition of ovine COX-1 assessed as reduction in PGE2 level using 250 nM arachidonic acid as substrate preincubated with enzyme for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Institute of Experimental Botany of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50555910(CHEMBL469433)
Affinity DataIC50: 2.00E+4nMAssay Description:Competitive inhibition of ovine COX-1 assessed as reduction in PGE2 level using 1250 nM arachidonic acid as substrate preincubated with enzyme for 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Institute of Experimental Botany of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50555910(CHEMBL469433)
Affinity DataIC50: 710nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 5 to 80 uM arachidonic acid as substrate preincubated with enzyme for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed