BDBM50555568 CHEMBL4787451

SMILES CCN(C)C(=O)Oc1ccc(cc1)-c1cc(=O)c2c(OC(=O)N(C)CC)cc(OC(=O)N(C)CC)cc2o1

InChI Key InChIKey=MBGXXUPMENAELF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50555568   

TargetAcetylcholinesterase(Rat)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50555568(CHEMBL4787451)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50555568(CHEMBL4787451)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of rat serum BChE using acetylthiocholine iodide as substrate measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50555568(CHEMBL4787451)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetCholinesterase(Human)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50555568(CHEMBL4787451)
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of human serum BChE using acetylthiocholine iodide as substrate measured after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50555568(CHEMBL4787451)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine as substrate incubated for 15 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCarboxylic ester hydrolase(Rat)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50555568(CHEMBL4787451)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of rat serum Butyrylcholine esterase using butyrylthiocholine as substrate incubated for 15 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50555568(CHEMBL4787451)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine as substrate incubated for 15 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Nanyang Normal University

Curated by ChEMBL
LigandPNGBDBM50555568(CHEMBL4787451)
Affinity DataIC50: 2.06E+4nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine as substrate incubated for 15 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed