BDBM50555229 CHEMBL4757863

SMILES c1cnc(cc1OCC(F)F)Cn2cnc3c2nc(nc3N)Cl

InChI Key InChIKey=SYPCZSDQCBMLSV-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50555229   

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50555229(CHEMBL4757863)Copy SMILESCopy InChI

Affinity DataIC50: 360nMAssay Description:Inhibition of PDE8A1 (480 to 820 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cAMP substrate incubated for 15 mins by liq...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/25/2022
Entry Details Article
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