BDBM50555100 CHEMBL4749457

SMILES Cc1noc(C)c1-c1[nH]ncc1-c1ccncc1

InChI Key InChIKey=JYTPHNOPQGAILG-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50555100   

TargetHistone-lysine N-methyltransferase NSD3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50555100(CHEMBL4749457)
Affinity DataKd:  3.00E+5nMAssay Description:Binding affinity to NSD3 PWWP1 domain (263 to 398 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50555100(CHEMBL4749457)
Affinity DataKd:  3.00E+5nMAssay Description:Binding affinity to recombinant human NSD3 PWWP1 domain (247 to 398 residues) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50555100(CHEMBL4749457)
Affinity DataKd:  3.00E+5nMAssay Description:Inhibition of NSD3 PWWP1 domain (unknown origin) assessed as inhibition constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50555100(CHEMBL4749457)
Affinity DataKd:  3.30E+5nMAssay Description:Binding affinity to human NSD3 PWWP1 domain assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed