BDBM50554960 CHEMBL4749555

SMILES N[C@@H](CCNS(=O)(=O)c1ccc(cc1C(F)(F)F)C#N)COc1ccc(C#N)c(F)c1

InChI Key InChIKey=UMZFBKPGPOOUGI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50554960   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50554960(CHEMBL4749555)Copy SMILESCopy InChI

Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at human TRPV4 expressed in BHK or HEK MSR2 cells assessed as inhibition of TRPV4 agonist GSK634775 (EC80)-induced response incub...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/25/2022
Entry Details Article
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