BDBM50554925 CHEMBL4792434::US20240059655, Compound PW0894

SMILES COc1cccc(Cc2cc(ncn2)N2CCc3c2cccc3C(=O)NCCO)c1

InChI Key InChIKey=HBQOBOFTIDPSBT-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50554925   

TargetG-protein coupled receptor 52(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50554925(CHEMBL4792434 | US20240059655, Compound PW0894)
Affinity DataEC50:  351nMAssay Description:Agonist activity at human GPR52 expressed in HEK293 cells assessed as increase in cAMP levels incubated for 15 mins by Glosensor cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 52(Mouse)
University Of Texas

US Patent
LigandPNGBDBM50554925(CHEMBL4792434 | US20240059655, Compound PW0894)
Affinity DataEC50:  131nMAssay Description:In Vitro Evaluation of GPR52 Activation. Newly synthesized compounds were evaluated in a twelve-point concentration-response for GPR52 agonist activi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent

TargetG-protein coupled receptor 52(Mouse)
University Of Texas

US Patent
LigandPNGBDBM50554925(CHEMBL4792434 | US20240059655, Compound PW0894)
Affinity DataEC50:  351nMAssay Description:In Vitro Evaluation of GPR52 Activation. Newly synthesized compounds were evaluated in a twelve-point concentration-response for GPR52 agonist activi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent

TargetG-protein coupled receptor 52(Mouse)
University Of Texas

US Patent
LigandPNGBDBM50554925(CHEMBL4792434 | US20240059655, Compound PW0894)
Affinity DataEC50:  351nMAssay Description:In Vitro Evaluation of GPR52 Activation. Newly synthesized compounds were evaluated in a twelve-point concentration-response for GPR52 agonist activi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent