BDBM50554922 CHEMBL4761816::US20240059655, Compound PW0753

SMILES OCCNC(=O)c1cccc2N(CCc12)c1nccc(n1)C(=O)c1cc(F)cc(c1)C(F)(F)F

InChI Key InChIKey=IYYHBQUEQSSSID-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50554922   

TargetG-protein coupled receptor 52(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50554922(CHEMBL4761816 | US20240059655, Compound PW0753)
Affinity DataEC50:  1.59E+3nMAssay Description:Agonist activity at human GPR52 expressed in HEK293 cells assessed as increase in cAMP levels incubated for 15 mins by Glosensor cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 52(Mouse)
University Of Texas

US Patent
LigandPNGBDBM50554922(CHEMBL4761816 | US20240059655, Compound PW0753)
Affinity DataEC50:  1.59E+3nMAssay Description:In Vitro Evaluation of GPR52 Activation. Newly synthesized compounds were evaluated in a twelve-point concentration-response for GPR52 agonist activi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent

TargetG-protein coupled receptor 52(Mouse)
University Of Texas

US Patent
LigandPNGBDBM50554922(CHEMBL4761816 | US20240059655, Compound PW0753)
Affinity DataEC50:  1.59E+3nMAssay Description:In Vitro Evaluation of GPR52 Activation. Newly synthesized compounds were evaluated in a twelve-point concentration-response for GPR52 agonist activi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent