BDBM50554841 CHEMBL4785020

SMILES CC(C)n1c2[nH]c3cc(ccc3c2c(=O)c2cc(F)c(N3CCN(C)CC3)c(F)c12)C#N

InChI Key InChIKey=SZUXODKNQVFHOH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50554841   

TargetALK tyrosine kinase receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50554841(CHEMBL4785020)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of N-terminal GST tagged wild-type human ALK cytoplasmic domain (1058-1620 amino acids) expressed Sf9 cells pre-incubated for 30 mins befo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed