BDBM50554826 CHEMBL4776403

SMILES COc1cc2c(c(F)c1C1CCN(CC1)C1COC1)n(C(C)C)c1[nH]c3cc(ccc3c1c2=O)C#N

InChI Key InChIKey=WORIXDKKDQDLGS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50554826   

TargetALK tyrosine kinase receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50554826(CHEMBL4776403)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of N-terminal GST tagged wild-type human ALK cytoplasmic domain (1058-1620 amino acids) expressed Sf9 cells pre-incubated for 30 mins befo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed