BDBM50554822 CHEMBL4779307

SMILES COc1cc2c(c(F)c1N1CCNC(C)(C)C1)n(C(C)C)c1[nH]c3cc(ccc3c1c2=O)C#N

InChI Key InChIKey=OHTBDNXLPXHGBS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50554822   

TargetALK tyrosine kinase receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50554822(CHEMBL4779307)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of N-terminal GST tagged wild-type human ALK cytoplasmic domain (1058-1620 amino acids) expressed Sf9 cells pre-incubated for 30 mins befo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed