BDBM50554662 CHEMBL4799966

SMILES CC(C)C[C@@H](CN(CC(=O)N[C@@H](C)C(N)=O)S(C)(=O)=O)NC(=O)[C@H](CC(C)C)NC(=O)CN(C[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN(C[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)CN(C[C@@H](NC(=O)[C@H](CC(C)C)NC(C)=O)[C@@H](C)O)S(=O)(=O)Cc1ccccc1)S(=O)(=O)CC(C)C)S(=O)(=O)CCN

InChI Key InChIKey=AMJAQKVLBTZRHM-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50554662   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50554662(CHEMBL4799966)
Affinity DataKd:  653nMAssay Description:Binding affinity to human recombinant MDM2 (1 to 150 residue) expressed in Escherichia coli using presence of FITC-labelled compound by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50554662(CHEMBL4799966)
Affinity DataKd:  348nMAssay Description:Binding affinity to MDMX (unknown origin) by using FITC-labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed