BDBM50554657 CHEMBL4778122

SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6]-[#7](-[#6]-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]-[#6](=O)-[#6]-[#7](-[#6]-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7](-[#6]-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6](-[#7]-[#6](-[#6])=O)-[#6@H](-[#6])-[#8])S([#6])(=O)=O)S(=O)(=O)c1ccc(cc1)-[#6](=[#6](\c1ccccc1)-c1ccccc1)\c1ccccc1)S(=O)(=O)[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6]-[#7](-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](-[#7])=O)S([#6])(=O)=O

InChI Key InChIKey=ZZVZEQBDNONMDP-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50554657   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50554657(CHEMBL4778122)
Affinity DataKd:  62nMAssay Description:Binding affinity to human recombinant MDM2 (1 to 150 residue) expressed in Escherichia coli using presence of FITC-labelled compound by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProtein Mdm4(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50554657(CHEMBL4778122)
Affinity DataKd:  372nMAssay Description:Binding affinity to MDMX (unknown origin) by using FITC-labeled compound by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed