BDBM50554643 CHEMBL4763981

SMILES O=C(CCCCCN1CCC2C(C1)Nc1ccccc21)Nc1ccc(\C=C2/CCn3c2nc2ccccc2c3=O)cc1

InChI Key InChIKey=VFERHOUHYWLGSW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50554643   

TargetAcetylcholinesterase(Human)
Xinyang Normal University

Curated by ChEMBL
LigandPNGBDBM50554643(CHEMBL4763981)
Affinity DataIC50: 153nMAssay Description:Inhibition of human erythrocytes AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCholinesterase(Human)
Xinyang Normal University

Curated by ChEMBL
LigandPNGBDBM50554643(CHEMBL4763981)
Affinity DataIC50: 486nMAssay Description:Inhibition of human serum BuChe by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Xinyang Normal University

Curated by ChEMBL
LigandPNGBDBM50554643(CHEMBL4763981)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) self aggregation incubated for 48 hrs by thioflavin-T fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed