BDBM50554338 CHEMBL4791640

SMILES Nc1n[nH]c(n1)N1CCC(CC1)N1CCS(=O)(=O)C[C@@H]1Cc1ccc(Cl)cc1

InChI Key InChIKey=CCZUIJXVLDHFRC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50554338   

TargetChitotriosidase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554338(CHEMBL4791640)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of full-length C-terminal his-tagged human recombinant CHIT1 catalytic domain (1 to 386 residues) expressed in HEK293F cells assessed as r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetChitotriosidase-1(Mouse)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554338(CHEMBL4791640)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant full-length C-terminal his-tagged mouse CHIT1 expressed in CHO-K1 cells assessed as reduction in chitinolytic activity usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetAcidic mammalian chitinase(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554338(CHEMBL4791640)
Affinity DataIC50: 850nMAssay Description:Inhibition of full-length C-terminal his-tagged human AMCase expressed in CHO-K1 cells assessed as reduction in chitinolytic activity using 4-methylu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetAcidic mammalian chitinase(Mouse)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50554338(CHEMBL4791640)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of full-length C-terminal his-tagged mouse AMCase expressed in expressed in CHO-K1 cells assessed as reduction in chitinolytic activity us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed