BDBM50554305 CHEMBL4776795

SMILES Cn1nc(cc1C(=O)N[C@@H](Cc1ccccc1)C(=O)NC1(CC1)C#N)C(C)(C)C

InChI Key InChIKey=FWDHQPCCEQRRCZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50554305   

TargetProcathepsin L(Human)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50554305(CHEMBL4776795)
Affinity DataKi:  5nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50554305(CHEMBL4776795)
Affinity DataKi:  63nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50554305(CHEMBL4776795)
Affinity DataKi:  63nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed