BDBM50554296 CHEMBL4799785

SMILES Oc1ccc(C[C@H](NC(=O)c2ccccc2)C(=O)NCC#N)cc1

InChI Key InChIKey=QDXJMPRQUCWKKV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50554296   

TargetProcathepsin L(Human)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50554296(CHEMBL4799785)
Affinity DataKi:  79nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50554296(CHEMBL4799785)
Affinity DataKi:  199nMAssay Description:Binding affinity to Trypanosoma cruzi Cruzain assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal Do Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50554296(CHEMBL4799785)
Affinity DataKi:  200nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed