BDBM50554281 CHEMBL4762612

SMILES CSCC[C@H](NC(=O)[C@H](C)NC(=O)CN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@H]1CSCC(=O)NCCCCNC(=O)CSC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)C(CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CCCCNC(=O)c1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc12)C(N)=O

InChI Key InChIKey=RGOZTFOMYNANNJ-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50554281   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Tokyo Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50554281(CHEMBL4762612)
Affinity DataKd:  1.78E+5nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Tokyo Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50554281(CHEMBL4762612)
Affinity DataKd:  5.71E+5nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constant in presence of 50 uM p53 peptide by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed