BDBM50554225 CHEMBL4744156

SMILES CNc1cc(F)cc2c(O)c(C(=O)Nc3ccc(cc3)C(O)=O)c(=O)[nH]c12

InChI Key InChIKey=ACSDSFPAGHERCC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50554225   

TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50554225(CHEMBL4744156)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50554225(CHEMBL4744156)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 2alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50554225(CHEMBL4744156)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by Q-patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed