BDBM50554224 CHEMBL4743075

SMILES CNc1cc(F)cc2c(NCCN3CCOCC3)c(C(=O)Nc3ccc(cc3)C(O)=O)c(=O)[nH]c12

InChI Key InChIKey=NKCCKBBSHMGYMD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50554224   

TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50554224(CHEMBL4743075)
Affinity DataIC50: 15nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed