BDBM50554206 CHEMBL4798088

SMILES CCCCCN(CCCCC)Cc1cc(ccc1NC(=O)c1cc2cc(F)cc(NC)c2[nH]c1=O)C(O)=O

InChI Key InChIKey=DFZMJDOPWZIKHC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50554206   

TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50554206(CHEMBL4798088)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Escherichia coli DNA gyrase by measuring supercoiling activity incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50554206(CHEMBL4798088)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 2alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50554206(CHEMBL4798088)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by Q-patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed