BDBM50554126 CHEMBL4777408

SMILES CC(C)(COC(=O)CCC(=O)OC[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCS

InChI Key InChIKey=DFNKSCRPOZETMX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50554126   

TargetAurora kinase A(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50554126(CHEMBL4777408)
Affinity DataIC50: 8.30E+4nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) using myelin basic protein as substrate incubated for 30 mins in presence or absence of DTT by [g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50554126(CHEMBL4777408)
Affinity DataIC50: 7.31E+5nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) using myelin basic protein as substrate incubated for 30 mins in presence of DTT by [gamma-33P]-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50554126(CHEMBL4777408)
Affinity DataIC50: 1.17E+5nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) using myelin basic protein as substrate incubated for 30 mins in absence of DTT by [gamma-33P]-AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed