BDBM50553911 CHEMBL4764712

SMILES COC(=O)CNC(=O)Nc1c2CCCc2cc2CCCc12

InChI Key InChIKey=GPEUSHWTEKFXMA-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50553911   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Nodthera

Curated by ChEMBL

LigandBDBM50553911(CHEMBL4764712)Copy SMILESCopy InChI

Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of NLRP3 in human PBMC cells assessed as inhibition of LPS and ATP-induced IL-1beta productionMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/25/2022
Entry Details Article
Copy Entry DOIPubMed
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TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Nodthera

Curated by ChEMBL

LigandBDBM50553911(CHEMBL4764712)Copy SMILESCopy InChI

Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of NLRP3 in LPS/nigericin-induced human THP-1 cells assessed as inhibition of IL-1beta production pretreated with LPS for 3 hrs followed b...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/18/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL