BDBM50553814 CHEMBL4795449

SMILES CN1C(=O)CCC(N2C(=O)c3cccc(NCCNC(=O)CCCCCCCCCCC(=O)N4CCN(CC4)C(=O)c4cc(Cc5n[nH]c(=O)c6ccccc56)ccc4F)c3C2=O)C1=O

InChI Key InChIKey=BFHBWQUTCXAXMP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50553814   

TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50553814(CHEMBL4795449)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant human C-terminal His-tagged PARP1 expressed in Sf9 insect cells preincubated for 20 mins in presence of activated DNA follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed