BDBM50553728 CHEMBL4757321

SMILES FC(F)(F)c1ccc2[nH]c(nc2c1)-c1c(Cl)cc(cc1Cl)-c1cn[nH]c1

InChI Key InChIKey=ZIKYUANMKZISMZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50553728   

TargetNeuropeptides B/W receptor type 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50553728(CHEMBL4757321)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human NPBWR1 assessed as inhibition of agonist-induced cAMP accumulation by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetNeuropeptides B/W receptor type 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50553728(CHEMBL4757321)
Affinity DataIC50: 30nMAssay Description:Negative allosteric modulation activity at NPBWR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed