BDBM50553555 CHEMBL4758366

SMILES CNC(=O)N1CCCc2ccc(NC(=O)c3cccc(c3)-c3ccncc3)cc12

InChI Key InChIKey=FKQOEFTVOPIHMO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50553555   

TargetCREB-binding protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50553555(CHEMBL4758366)
Affinity DataIC50: 213nMAssay Description:Inhibition of GST-tagged CBP BRD (unknown origin) incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50553555(CHEMBL4758366)
Affinity DataIC50: 63nMAssay Description:Inhibition of CBP BRD (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50553555(CHEMBL4758366)
Affinity DataIC50: 60nMAssay Description:Inhibition of GST-tagged CBP bromodomain (1082 to 1197 residue) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using SGRG-K(Ac)-GG-K ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed