BDBM50553250 CHEMBL4786331

SMILES [H][C@]1(CCN(C1)c1c(F)cc2c3oc(C)nc3c(=O)n(C3CC3)c2c1Cl)[C@H](C)N

InChI Key InChIKey=LOCSNCVSEDLFDP-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50553250   

TargetCytochrome P450 1A2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50553250(CHEMBL4786331)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50553250(CHEMBL4786331)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50553250(CHEMBL4786331)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50553250(CHEMBL4786331)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50553250(CHEMBL4786331)
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50553250(CHEMBL4786331)
Affinity DataIC50: 2.87E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50553250(CHEMBL4786331)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin) by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50553250(CHEMBL4786331)
Affinity DataIC50: 9.36E+4nMAssay Description:Inhibition of Cav1.2 (unknown origin) by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50553250(CHEMBL4786331)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using relaxed pBR322 as substrate incubated for 30 mins by ethidium bromide staining based gel electro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A/B(Staphylococcus aureus)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50553250(CHEMBL4786331)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase IV using kDNA as substrate incubated for 30 mins by ethidium bromide staining based gel electrophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed