BDBM50553095 CHEMBL4745618

SMILES N[C@H]1CCC(=O)NCC[C@H](NC(=O)C[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1CC(O)=O

InChI Key InChIKey=YPOQRJZHCULELI-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50553095   

TargetInterleukin-1 receptor antagonist protein(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50553095(CHEMBL4745618)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of recombinant full length human IRAP expressed in HEK293T cells assessed as substrate cleavage using Leu-MCA as substrate by fluorogenic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50553095(CHEMBL4745618)
Affinity DataKi:  674nMAssay Description:Binding affinity to recombinant full length human IRAP expressed in HEK293T cells using Leu-MCA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed