BDBM50553079 CHEMBL4749888

SMILES Brc1ccc2occ(C(=O)NC3CCN(Cc4ccccc4)CC3)c(=O)c2c1

InChI Key InChIKey=WWMJGNGNARFWEL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50553079   

TargetAcetylcholinesterase(Electric eel)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553079(CHEMBL4749888)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 6 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553079(CHEMBL4749888)
Affinity DataIC50: 9.45E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 6 mins followed by substrate addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553079(CHEMBL4749888)
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate preincubated with enzyme for 15 mins followed incubation with substrate for 20 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed