BDBM50552715 CHEMBL4753114::US11591329, Ex. No. 5

SMILES CC(C)C1N(CCN(C)C1=O)c1ccc2[nH]nc(-c3cnn(C)c3)c2n1

InChI Key InChIKey=PIVRALLDQVUVCH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552715   

TargetFibroblast growth factor receptor 3(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50552715(CHEMBL4753114 | US11591329, Ex. No. 5)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged FGFR3 (447 to 761 residues) expressed in Sf21 cells using biotinylated EQEDEPEGDYFEWLE peptide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50552715(CHEMBL4753114 | US11591329, Ex. No. 5)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
Go to US Patent