BDBM50552554 CHEMBL4797657

SMILES CC(C)c1cc(ccc1OC)Oc2c(cc(cc2Cl)CO)Cl

InChI Key InChIKey=YJBUGSRJCVSLKC-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552554   

TargetNuclear receptor ROR-gamma(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50552554(CHEMBL4797657)
Affinity DataEC50:  332nMAssay Description:Agonist activity at Gal4-fused RORgammat (unknown origin) expressed in Jurkat cells by reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThyroid hormone receptor beta(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50552554(CHEMBL4797657)
Affinity DataEC50:  54nMAssay Description:Agonist activity at human TRbeta1 CHO-K1 cells by reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed