BDBM50552500 CHEMBL4743459

SMILES OC[C@H]1CCCN1Cc1ccc(Oc2ccc(cc2)-c2cccc(c2)C(F)(F)F)cc1

InChI Key InChIKey=WEHWPLQOHFRDMZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552500   

TargetSphingosine kinase 1(Human)
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50552500(CHEMBL4743459)
Affinity DataEC50:  299nMAssay Description:Inhibition of human SphK1 expressed in Saccharomyces cerevisiae KYA1 assessed as yeast growth at 30 degreeC measured after 24 to 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetSphingosine kinase 2(Human)
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50552500(CHEMBL4743459)
Affinity DataEC50:  488nMAssay Description:Inhibition of human SphK2 expressed in Saccharomyces cerevisiae KYA1 assessed as yeast growth at 30 degreeC measured after 24 to 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed