BDBM50552135 CHEMBL4303210

SMILES CNc1ccc(cc1-n1cnc(c1)-c1ccc(cc1)C(F)(F)F)[N+]([O-])=O

InChI Key InChIKey=LITXVDAFEYLWQE-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552135   

TargetToll-like receptor 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50552135(CHEMBL4303210)
Affinity DataIC50: 54nMAssay Description:Inhibition of Rho-Pam3 binding to TLR1 (unknown origin)/human TLR2 expressed in HEK293 cells incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetToll-like receptor 1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50552135(CHEMBL4303210)
Affinity DataEC50:  5.20E+3nMAssay Description:Agonist activity at TLR2/TLR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed