BDBM50552018 CHEMBL4764100

SMILES CN1CCN(CC1)C(=S)SCC(=O)Nc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=SMLRBEBCNCWDHG-UHFFFAOYSA-N

Data  6 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50552018   

TargetCarbonic anhydrase 1(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50552018(CHEMBL4764100)
Affinity DataIC50: 152nMAssay Description:Inhibition of human erythrocyte CA1 using 4-nitrophenyl acetate as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50552018(CHEMBL4764100)
Affinity DataIC50: 28nMAssay Description:Inhibition of human erythrocyte CA2 using 4-nitrophenyl acetate as substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50552018(CHEMBL4764100)
Affinity DataKi:  7.40nMAssay Description:Inhibition of human carbonic anhydrase 2 assessed as inhibition constant preincubated for 15 mins and measured for 10 to 100 sec by phenol red dye ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50552018(CHEMBL4764100)
Affinity DataKi:  21nMAssay Description:Inhibition of human erythrocyte CA2 using 4-nitrophenyl acetate as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50552018(CHEMBL4764100)
Affinity DataKi:  66nMAssay Description:Inhibition of human carbonic anhydrase 1 assessed as inhibition constant preincubated for 15 mins and measured for 10 to 100 sec by phenol red dye ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50552018(CHEMBL4764100)
Affinity DataKi:  98nMAssay Description:Inhibition of human erythrocyte CA1 b using 4-nitrophenyl acetate as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50552018(CHEMBL4764100)
Affinity DataKi:  255nMAssay Description:Inhibition of human carbonic anhydrase 9 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCarbonic anhydrase 4(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50552018(CHEMBL4764100)
Affinity DataKi:  420nMAssay Description:Inhibition of human carbonic anhydrase 4 assessed as inhibition constant preincubated for 15 mins and measured for 10 to 100 sec by phenol red dye ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed